Drug Interactions
Comprehensive guide to drug-drug interactions, pharmacokinetic interactions, and interaction management.
Browse the pages below for detailed information.
(-)-adrenaline — α1D-adrenoceptor Interaction
Drug-target interaction between (-)-adrenaline and α1D-adrenoceptor. Metabolite pharmacological agent targeting this protein.
(-)-adrenaline — α2A-adrenoceptor Interaction
Drug-target interaction between (-)-adrenaline and α2A-adrenoceptor. Metabolite pharmacological agent targeting this protein.
(-)-menthol — TRPM8 Interaction
Drug-target interaction between (-)-menthol and TRPM8. Natural product pharmacological agent targeting this protein.
(-)-noradrenaline — α2B-adrenoceptor Interaction
Drug-target interaction between (-)-noradrenaline and α2B-adrenoceptor. Metabolite pharmacological agent targeting this protein.
(-)-noradrenaline — α2C-adrenoceptor Interaction
Drug-target interaction between (-)-noradrenaline and α2C-adrenoceptor. Metabolite pharmacological agent targeting this protein.
(-)-pentazocine — sigma non-opioid intracellular receptor 1 Interaction
Drug-target interaction between (-)-pentazocine and sigma non-opioid intracellular receptor 1. Synthetic organic pharmacological agent targeting this protein.
(-)-sulpiride — D2 receptor Interaction
Drug-target interaction between (-)-sulpiride and D2 receptor. Synthetic organic pharmacological agent targeting this protein.
(-)-sulpiride — D3 receptor Interaction
Drug-target interaction between (-)-sulpiride and D3 receptor. Synthetic organic pharmacological agent targeting this protein.
(R)-cetirizine — H1 receptor Interaction
Drug-target interaction between (R)-cetirizine and H1 receptor. Synthetic organic pharmacological agent targeting this protein.
Δ9-tetrahydrocannabinol — CB1 receptor Interaction
Drug-target interaction between Δ9-tetrahydrocannabinol and CB1 receptor. Natural product pharmacological agent targeting this protein.
1,25-dihydroxyvitamin D3 — Vitamin D receptor Interaction
Drug-target interaction between 1,25-dihydroxyvitamin D3 and Vitamin D receptor. Metabolite pharmacological agent targeting this protein.
17β-estradiol — Estrogen receptor-α Interaction
Drug-target interaction between 17β-estradiol and Estrogen receptor-α. Metabolite pharmacological agent targeting this protein.
6-aminocaproic acid — plasminogen Interaction
Drug-target interaction between 6-aminocaproic acid and plasminogen. Synthetic organic pharmacological agent targeting this protein.
abaloparatide — PTH1 receptor Interaction
Drug-target interaction between abaloparatide and PTH1 receptor. Peptide pharmacological agent targeting this protein.
abarelix — GnRH1 receptor Interaction
Drug-target interaction between abarelix and GnRH1 receptor. Peptide pharmacological agent targeting this protein.
abatacept — CD80 Interaction
Drug-target interaction between abatacept and CD80. Peptide pharmacological agent targeting this protein.
abatacept — CD86 Interaction
Drug-target interaction between abatacept and CD86. Peptide pharmacological agent targeting this protein.
abciximab — integrin αIIbβ3 Interaction
Drug-target interaction between abciximab and integrin αIIbβ3. Antibody pharmacological agent targeting this protein.
acalabrutinib — Bruton tyrosine kinase Interaction
Drug-target interaction between acalabrutinib and Bruton tyrosine kinase. Synthetic organic pharmacological agent targeting this protein.
acebutolol — β1-adrenoceptor Interaction
Drug-target interaction between acebutolol and β1-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
acetazolamide — carbonic anhydrase 7 Interaction
Drug-target interaction between acetazolamide and carbonic anhydrase 7. Synthetic organic pharmacological agent targeting this protein.
acetyldigitoxin — sodium/potassium-transporting ATPase subunit α-1 Interaction
Drug-target interaction between acetyldigitoxin and sodium/potassium-transporting ATPase subunit α-1. Synthetic organic pharmacological agent targeting this protein.
aclidinium — M3 receptor Interaction
Drug-target interaction between aclidinium and M3 receptor. Synthetic organic pharmacological agent targeting this protein.
adapalene — Retinoic acid receptor-β Interaction
Drug-target interaction between adapalene and Retinoic acid receptor-β. Synthetic organic pharmacological agent targeting this protein.
adapalene — Retinoic acid receptor-γ Interaction
Drug-target interaction between adapalene and Retinoic acid receptor-γ. Synthetic organic pharmacological agent targeting this protein.
adenosine — A1 receptor Interaction
Drug-target interaction between adenosine and A1 receptor. Metabolite pharmacological agent targeting this protein.
adenosine — A2A receptor Interaction
Drug-target interaction between adenosine and A2A receptor. Metabolite pharmacological agent targeting this protein.
afatinib — epidermal growth factor receptor Interaction
Drug-target interaction between afatinib and epidermal growth factor receptor. Synthetic organic pharmacological agent targeting this protein.
agomelatine — MT1 receptor Interaction
Drug-target interaction between agomelatine and MT1 receptor. Synthetic organic pharmacological agent targeting this protein.
agomelatine — MT2 receptor Interaction
Drug-target interaction between agomelatine and MT2 receptor. Synthetic organic pharmacological agent targeting this protein.
alectinib — ALK receptor tyrosine kinase Interaction
Drug-target interaction between alectinib and ALK receptor tyrosine kinase. Synthetic organic pharmacological agent targeting this protein.
alefacept — CD2 Interaction
Drug-target interaction between alefacept and CD2. Peptide pharmacological agent targeting this protein.
alemtuzumab — CD52 Interaction
Drug-target interaction between alemtuzumab and CD52. Antibody pharmacological agent targeting this protein.
alendronate — farnesyl diphosphate synthase Interaction
Drug-target interaction between alendronate and farnesyl diphosphate synthase. Synthetic organic pharmacological agent targeting this protein.
alfuzosin — α1A-adrenoceptor Interaction
Drug-target interaction between alfuzosin and α1A-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
alfuzosin — α1B-adrenoceptor Interaction
Drug-target interaction between alfuzosin and α1B-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
alfuzosin — α1D-adrenoceptor Interaction
Drug-target interaction between alfuzosin and α1D-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
alirocumab — proprotein convertase subtilisin/kexin type 9 Interaction
Drug-target interaction between alirocumab and proprotein convertase subtilisin/kexin type 9. Antibody pharmacological agent targeting this protein.
aliskiren — renin Interaction
Drug-target interaction between aliskiren and renin. Synthetic organic pharmacological agent targeting this protein.
alitretinoin — Retinoic acid receptor-α Interaction
Drug-target interaction between alitretinoin and Retinoic acid receptor-α. Metabolite pharmacological agent targeting this protein.
alitretinoin — Retinoic acid receptor-β Interaction
Drug-target interaction between alitretinoin and Retinoic acid receptor-β. Metabolite pharmacological agent targeting this protein.
alitretinoin — Retinoic acid receptor-γ Interaction
Drug-target interaction between alitretinoin and Retinoic acid receptor-γ. Metabolite pharmacological agent targeting this protein.
alitretinoin — vitamin K epoxide reductase complex subunit 1 Interaction
Drug-target interaction between alitretinoin and vitamin K epoxide reductase complex subunit 1. Metabolite pharmacological agent targeting this protein.
allopurinol — xanthine dehydrogenase Interaction
Drug-target interaction between allopurinol and xanthine dehydrogenase. Synthetic organic pharmacological agent targeting this protein.
alogliptin — dipeptidyl peptidase 4 Interaction
Drug-target interaction between alogliptin and dipeptidyl peptidase 4. Synthetic organic pharmacological agent targeting this protein.
alosetron — 5-HT3A Interaction
Drug-target interaction between alosetron and 5-HT3A. Synthetic organic pharmacological agent targeting this protein.
alpelisib — phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Interaction
Drug-target interaction between alpelisib and phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha. Synthetic organic pharmacological agent targeting this protein.
alpha-methyltyrosine — L-Tyrosine hydroxylase Interaction
Drug-target interaction between alpha-methyltyrosine and L-Tyrosine hydroxylase. Synthetic organic pharmacological agent targeting this protein.
alpha1-proteinase inhibitor — elastase, neutrophil expressed Interaction
Drug-target interaction between alpha1-proteinase inhibitor and elastase, neutrophil expressed. Peptide pharmacological agent targeting this protein.
alprenolol — β2-adrenoceptor Interaction
Drug-target interaction between alprenolol and β2-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
alvimopan — μ receptor Interaction
Drug-target interaction between alvimopan and μ receptor. Synthetic organic pharmacological agent targeting this protein.
amantadine — GluN2A Interaction
Drug-target interaction between amantadine and GluN2A. Synthetic organic pharmacological agent targeting this protein.
amantadine — GluN2B Interaction
Drug-target interaction between amantadine and GluN2B. Synthetic organic pharmacological agent targeting this protein.
amantadine — GluN2C Interaction
Drug-target interaction between amantadine and GluN2C. Synthetic organic pharmacological agent targeting this protein.
amantadine — GluN2D Interaction
Drug-target interaction between amantadine and GluN2D. Synthetic organic pharmacological agent targeting this protein.
ambrisentan — ETA receptor Interaction
Drug-target interaction between ambrisentan and ETA receptor. Synthetic organic pharmacological agent targeting this protein.
amiloride — ENaCαβγ Interaction
Drug-target interaction between amiloride and ENaCαβγ. Synthetic organic pharmacological agent targeting this protein.
aminoglutethimide — CYP19A1 Interaction
Drug-target interaction between aminoglutethimide and CYP19A1. Synthetic organic pharmacological agent targeting this protein.
amisulpride — D2 receptor Interaction
Drug-target interaction between amisulpride and D2 receptor. Synthetic organic pharmacological agent targeting this protein.
amitriptyline — H1 receptor Interaction
Drug-target interaction between amitriptyline and H1 receptor. Synthetic organic pharmacological agent targeting this protein.