Drug Interactions
Comprehensive guide to drug-drug interactions, pharmacokinetic interactions, and interaction management.
Browse the pages below for detailed information.
sildenafil — phosphodiesterase 5A Interaction
Drug-target interaction between sildenafil and phosphodiesterase 5A. Synthetic organic pharmacological agent targeting this protein.
silodosin — α1A-adrenoceptor Interaction
Drug-target interaction between silodosin and α1A-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
simeprevir — Hepatitis C virus genome polyprotein Interaction
Drug-target interaction between simeprevir and Hepatitis C virus genome polyprotein. Synthetic organic pharmacological agent targeting this protein.
simvastatin — hydroxymethylglutaryl-CoA reductase Interaction
Drug-target interaction between simvastatin and hydroxymethylglutaryl-CoA reductase. Synthetic organic pharmacological agent targeting this protein.
sintilimab — programmed cell death 1 (CD279) Interaction
Drug-target interaction between sintilimab and programmed cell death 1 (CD279). Antibody pharmacological agent targeting this protein.
siponimod — S1P1 receptor Interaction
Drug-target interaction between siponimod and S1P1 receptor. Synthetic organic pharmacological agent targeting this protein.
siponimod — S1P5 receptor Interaction
Drug-target interaction between siponimod and S1P5 receptor. Synthetic organic pharmacological agent targeting this protein.
sirolimus — FKBP prolyl isomerase 1A Interaction
Drug-target interaction between sirolimus and FKBP prolyl isomerase 1A. Synthetic organic pharmacological agent targeting this protein.
sitagliptin — dipeptidyl peptidase 4 Interaction
Drug-target interaction between sitagliptin and dipeptidyl peptidase 4. Synthetic organic pharmacological agent targeting this protein.
sitaxsentan — ETA receptor Interaction
Drug-target interaction between sitaxsentan and ETA receptor. Synthetic organic pharmacological agent targeting this protein.
sivelestat — elastase, neutrophil expressed Interaction
Drug-target interaction between sivelestat and elastase, neutrophil expressed. Synthetic organic pharmacological agent targeting this protein.
solifenacin — M2 receptor Interaction
Drug-target interaction between solifenacin and M2 receptor. Synthetic organic pharmacological agent targeting this protein.
solifenacin — M3 receptor Interaction
Drug-target interaction between solifenacin and M3 receptor. Synthetic organic pharmacological agent targeting this protein.
sonidegib — SMO Interaction
Drug-target interaction between sonidegib and SMO. Synthetic organic pharmacological agent targeting this protein.
sorafenib — fms related receptor tyrosine kinase 3 Interaction
Drug-target interaction between sorafenib and fms related receptor tyrosine kinase 3. Synthetic organic pharmacological agent targeting this protein.
sorafenib — kinase insert domain receptor Interaction
Drug-target interaction between sorafenib and kinase insert domain receptor. Synthetic organic pharmacological agent targeting this protein.
sorafenib — KIT proto-oncogene, receptor tyrosine kinase Interaction
Drug-target interaction between sorafenib and KIT proto-oncogene, receptor tyrosine kinase. Synthetic organic pharmacological agent targeting this protein.
sotagliflozin — Sodium/glucose cotransporter 1 Interaction
Drug-target interaction between sotagliflozin and Sodium/glucose cotransporter 1. Synthetic organic pharmacological agent targeting this protein.
sotagliflozin — Sodium/glucose cotransporter 2 Interaction
Drug-target interaction between sotagliflozin and Sodium/glucose cotransporter 2. Synthetic organic pharmacological agent targeting this protein.
sotalol — β1-adrenoceptor Interaction
Drug-target interaction between sotalol and β1-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
sotalol — β2-adrenoceptor Interaction
Drug-target interaction between sotalol and β2-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
sparsentan — AT1 receptor Interaction
Drug-target interaction between sparsentan and AT1 receptor. Synthetic organic pharmacological agent targeting this protein.
sparsentan — ETA receptor Interaction
Drug-target interaction between sparsentan and ETA receptor. Synthetic organic pharmacological agent targeting this protein.
spirapril — Angiotensin-converting enzyme Interaction
Drug-target interaction between spirapril and Angiotensin-converting enzyme. Synthetic organic pharmacological agent targeting this protein.
spiraprilat — Angiotensin-converting enzyme Interaction
Drug-target interaction between spiraprilat and Angiotensin-converting enzyme. Synthetic organic pharmacological agent targeting this protein.
spironolactone — Mineralocorticoid receptor Interaction
Drug-target interaction between spironolactone and Mineralocorticoid receptor. Synthetic organic pharmacological agent targeting this protein.
stapokibart — Interleukin-4 receptor subunit α Interaction
Drug-target interaction between stapokibart and Interleukin-4 receptor subunit α. Antibody pharmacological agent targeting this protein.
succinylcholine — nicotinic acetylcholine receptor α1 subunit Interaction
Drug-target interaction between succinylcholine and nicotinic acetylcholine receptor α1 subunit. Synthetic organic pharmacological agent targeting this protein.
sufentanil — μ receptor Interaction
Drug-target interaction between sufentanil and μ receptor. Synthetic organic pharmacological agent targeting this protein.
sufinpyrazone — Urate anion exchanger 1 Interaction
Drug-target interaction between sufinpyrazone and Urate anion exchanger 1. Synthetic organic pharmacological agent targeting this protein.
sulpiride — D2 receptor Interaction
Drug-target interaction between sulpiride and D2 receptor. Synthetic organic pharmacological agent targeting this protein.
sumatriptan — 5-HT1B receptor Interaction
Drug-target interaction between sumatriptan and 5-HT1B receptor. Synthetic organic pharmacological agent targeting this protein.
sumatriptan — 5-HT1D receptor Interaction
Drug-target interaction between sumatriptan and 5-HT1D receptor. Synthetic organic pharmacological agent targeting this protein.
sunitinib — fms related receptor tyrosine kinase 4 Interaction
Drug-target interaction between sunitinib and fms related receptor tyrosine kinase 4. Synthetic organic pharmacological agent targeting this protein.
sunitinib — KIT proto-oncogene, receptor tyrosine kinase Interaction
Drug-target interaction between sunitinib and KIT proto-oncogene, receptor tyrosine kinase. Synthetic organic pharmacological agent targeting this protein.
sunitinib — platelet derived growth factor receptor beta Interaction
Drug-target interaction between sunitinib and platelet derived growth factor receptor beta. Synthetic organic pharmacological agent targeting this protein.
suprofen — COX-1 Interaction
Drug-target interaction between suprofen and COX-1. Synthetic organic pharmacological agent targeting this protein.
suprofen — COX-2 Interaction
Drug-target interaction between suprofen and COX-2. Synthetic organic pharmacological agent targeting this protein.
sutimlimab — complement C1s Interaction
Drug-target interaction between sutimlimab and complement C1s. Antibody pharmacological agent targeting this protein.
suvorexant — OX1 receptor Interaction
Drug-target interaction between suvorexant and OX1 receptor. Synthetic organic pharmacological agent targeting this protein.
suvorexant — OX2 receptor Interaction
Drug-target interaction between suvorexant and OX2 receptor. Synthetic organic pharmacological agent targeting this protein.
T4 — Thyroid hormone receptor-α Interaction
Drug-target interaction between T4 and Thyroid hormone receptor-α. Metabolite pharmacological agent targeting this protein.
T4 — Thyroid hormone receptor-β Interaction
Drug-target interaction between T4 and Thyroid hormone receptor-β. Metabolite pharmacological agent targeting this protein.
tacrine — acetylcholinesterase (Yt blood group) Interaction
Drug-target interaction between tacrine and acetylcholinesterase (Yt blood group). Synthetic organic pharmacological agent targeting this protein.
tacrine — butyrylcholinesterase Interaction
Drug-target interaction between tacrine and butyrylcholinesterase. Synthetic organic pharmacological agent targeting this protein.
tacrolimus — FKBP prolyl isomerase 1A Interaction
Drug-target interaction between tacrolimus and FKBP prolyl isomerase 1A. Synthetic organic pharmacological agent targeting this protein.
tadalafil — phosphodiesterase 5A Interaction
Drug-target interaction between tadalafil and phosphodiesterase 5A. Synthetic organic pharmacological agent targeting this protein.
tafasitamab — CD19 Interaction
Drug-target interaction between tafasitamab and CD19. Antibody pharmacological agent targeting this protein.
tafluprost — FP receptor Interaction
Drug-target interaction between tafluprost and FP receptor. Synthetic organic pharmacological agent targeting this protein.
talazoparib — poly(ADP-ribose) polymerase 1 Interaction
Drug-target interaction between talazoparib and poly(ADP-ribose) polymerase 1. Synthetic organic pharmacological agent targeting this protein.
talazoparib — poly(ADP-ribose) polymerase 2 Interaction
Drug-target interaction between talazoparib and poly(ADP-ribose) polymerase 2. Synthetic organic pharmacological agent targeting this protein.
tamibarotene — Retinoic acid receptor-α Interaction
Drug-target interaction between tamibarotene and Retinoic acid receptor-α. Synthetic organic pharmacological agent targeting this protein.
tamoxifen — Estrogen receptor-α Interaction
Drug-target interaction between tamoxifen and Estrogen receptor-α. Synthetic organic pharmacological agent targeting this protein.
tamsulosin — α1A-adrenoceptor Interaction
Drug-target interaction between tamsulosin and α1A-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
tamsulosin — α1B-adrenoceptor Interaction
Drug-target interaction between tamsulosin and α1B-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
tamsulosin — α1D-adrenoceptor Interaction
Drug-target interaction between tamsulosin and α1D-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.
tapentadol — μ receptor Interaction
Drug-target interaction between tapentadol and μ receptor. Synthetic organic pharmacological agent targeting this protein.
tapentadol — NET Interaction
Drug-target interaction between tapentadol and NET. Synthetic organic pharmacological agent targeting this protein.
tapinarof — aryl hydrocarbon receptor Interaction
Drug-target interaction between tapinarof and aryl hydrocarbon receptor. Synthetic organic pharmacological agent targeting this protein.
tasimelteon — MT1 receptor Interaction
Drug-target interaction between tasimelteon and MT1 receptor. Synthetic organic pharmacological agent targeting this protein.