Pharmaceutical Chemistry

Drug Interactions

Comprehensive guide to drug-drug interactions, pharmacokinetic interactions, and interaction management.

Browse the pages below for detailed information.

diazepam — GABAA receptor α1 subunit Interaction

Drug-target interaction between diazepam and GABAA receptor α1 subunit. Synthetic organic pharmacological agent targeting this protein.

diazepam — GABAA receptor α2 subunit Interaction

Drug-target interaction between diazepam and GABAA receptor α2 subunit. Synthetic organic pharmacological agent targeting this protein.

diazepam — GABAA receptor α3 subunit Interaction

Drug-target interaction between diazepam and GABAA receptor α3 subunit. Synthetic organic pharmacological agent targeting this protein.

diclofenac — COX-1 Interaction

Drug-target interaction between diclofenac and COX-1. Synthetic organic pharmacological agent targeting this protein.

diclofenac — COX-2 Interaction

Drug-target interaction between diclofenac and COX-2. Synthetic organic pharmacological agent targeting this protein.

dicumarol — vitamin K epoxide reductase complex subunit 1 Interaction

Drug-target interaction between dicumarol and vitamin K epoxide reductase complex subunit 1. Synthetic organic pharmacological agent targeting this protein.

dicyclomine — M1 receptor Interaction

Drug-target interaction between dicyclomine and M1 receptor. Synthetic organic pharmacological agent targeting this protein.

dicyclomine — M3 receptor Interaction

Drug-target interaction between dicyclomine and M3 receptor. Synthetic organic pharmacological agent targeting this protein.

diethylstilbestrol — Estrogen receptor-α Interaction

Drug-target interaction between diethylstilbestrol and Estrogen receptor-α. Synthetic organic pharmacological agent targeting this protein.

difelikefalin — κ receptor Interaction

Drug-target interaction between difelikefalin and κ receptor. Peptide pharmacological agent targeting this protein.

diflorasone diacetate — Glucocorticoid receptor Interaction

Drug-target interaction between diflorasone diacetate and Glucocorticoid receptor. Synthetic organic pharmacological agent targeting this protein.

difluprednate — Glucocorticoid receptor Interaction

Drug-target interaction between difluprednate and Glucocorticoid receptor. Synthetic organic pharmacological agent targeting this protein.

digitoxin — sodium/potassium-transporting ATPase subunit α-1 Interaction

Drug-target interaction between digitoxin and sodium/potassium-transporting ATPase subunit α-1. Synthetic organic pharmacological agent targeting this protein.

digoxin — sodium/potassium-transporting ATPase subunit α-1 Interaction

Drug-target interaction between digoxin and sodium/potassium-transporting ATPase subunit α-1. Natural product pharmacological agent targeting this protein.

dihydroergotamine — 5-HT1D receptor Interaction

Drug-target interaction between dihydroergotamine and 5-HT1D receptor. Synthetic organic pharmacological agent targeting this protein.

diltiazem — Cav1.1 Interaction

Drug-target interaction between diltiazem and Cav1.1. Synthetic organic pharmacological agent targeting this protein.

diphenhydramine — H1 receptor Interaction

Drug-target interaction between diphenhydramine and H1 receptor. Synthetic organic pharmacological agent targeting this protein.

dipyridamole — Equilibrative nucleoside transporter 1 Interaction

Drug-target interaction between dipyridamole and Equilibrative nucleoside transporter 1. Synthetic organic pharmacological agent targeting this protein.

disitamab vedotin — erb-b2 receptor tyrosine kinase 2 Interaction

Drug-target interaction between disitamab vedotin and erb-b2 receptor tyrosine kinase 2. Antibody pharmacological agent targeting this protein.

divozilimab — CD20 (membrane-spanning 4-domains, subfamily A, member 1) Interaction

Drug-target interaction between divozilimab and CD20 (membrane-spanning 4-domains, subfamily A, member 1). Antibody pharmacological agent targeting this protein.

dobutamine — β1-adrenoceptor Interaction

Drug-target interaction between dobutamine and β1-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.

docetaxel — tubulin beta class I Interaction

Drug-target interaction between docetaxel and tubulin beta class I. Synthetic organic pharmacological agent targeting this protein.

dofetilide — Kv11.1 Interaction

Drug-target interaction between dofetilide and Kv11.1. Synthetic organic pharmacological agent targeting this protein.

domperidone — D2 receptor Interaction

Drug-target interaction between domperidone and D2 receptor. Synthetic organic pharmacological agent targeting this protein.

domperidone — D3 receptor Interaction

Drug-target interaction between domperidone and D3 receptor. Synthetic organic pharmacological agent targeting this protein.

donepezil — acetylcholinesterase (Yt blood group) Interaction

Drug-target interaction between donepezil and acetylcholinesterase (Yt blood group). Synthetic organic pharmacological agent targeting this protein.

dopamine — D1 receptor Interaction

Drug-target interaction between dopamine and D1 receptor. Metabolite pharmacological agent targeting this protein.

dopamine — D2 receptor Interaction

Drug-target interaction between dopamine and D2 receptor. Metabolite pharmacological agent targeting this protein.

dopamine — D3 receptor Interaction

Drug-target interaction between dopamine and D3 receptor. Metabolite pharmacological agent targeting this protein.

dopamine — D4 receptor Interaction

Drug-target interaction between dopamine and D4 receptor. Metabolite pharmacological agent targeting this protein.

dopamine — D5 receptor Interaction

Drug-target interaction between dopamine and D5 receptor. Metabolite pharmacological agent targeting this protein.

dostarlimab — programmed cell death 1 (CD279) Interaction

Drug-target interaction between dostarlimab and programmed cell death 1 (CD279). Antibody pharmacological agent targeting this protein.

dosulepin — NET Interaction

Drug-target interaction between dosulepin and NET. Synthetic organic pharmacological agent targeting this protein.

dosulepin — SERT Interaction

Drug-target interaction between dosulepin and SERT. Synthetic organic pharmacological agent targeting this protein.

dotinurad — Urate anion exchanger 1 Interaction

Drug-target interaction between dotinurad and Urate anion exchanger 1. Synthetic organic pharmacological agent targeting this protein.

doxazosin — α1A-adrenoceptor Interaction

Drug-target interaction between doxazosin and α1A-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.

doxazosin — α1B-adrenoceptor Interaction

Drug-target interaction between doxazosin and α1B-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.

doxazosin — α1D-adrenoceptor Interaction

Drug-target interaction between doxazosin and α1D-adrenoceptor. Synthetic organic pharmacological agent targeting this protein.

doxepin — NET Interaction

Drug-target interaction between doxepin and NET. Synthetic organic pharmacological agent targeting this protein.

doxepin — SERT Interaction

Drug-target interaction between doxepin and SERT. Synthetic organic pharmacological agent targeting this protein.

doxycycline — MMP7 Interaction

Drug-target interaction between doxycycline and MMP7. Synthetic organic pharmacological agent targeting this protein.

dromostanolone propionate — Androgen receptor Interaction

Drug-target interaction between dromostanolone propionate and Androgen receptor. Synthetic organic pharmacological agent targeting this protein.

drospirenone — Mineralocorticoid receptor Interaction

Drug-target interaction between drospirenone and Mineralocorticoid receptor. Synthetic organic pharmacological agent targeting this protein.

drotrecogin alfa — coagulation factor V Interaction

Drug-target interaction between drotrecogin alfa and coagulation factor V. Peptide pharmacological agent targeting this protein.

drotrecogin alfa — coagulation factor VIII Interaction

Drug-target interaction between drotrecogin alfa and coagulation factor VIII. Peptide pharmacological agent targeting this protein.

Drug-Drug Interactions Overview

Drug-drug interactions occur when one drug affects the pharmacokinetics or pharmacodynamics of another drug, leading to altered therapeutic effects or toxicity.

duloxetine — NET Interaction

Drug-target interaction between duloxetine and NET. Synthetic organic pharmacological agent targeting this protein.

duloxetine — SERT Interaction

Drug-target interaction between duloxetine and SERT. Synthetic organic pharmacological agent targeting this protein.

dupilumab — Interleukin-4 receptor subunit α Interaction

Drug-target interaction between dupilumab and Interleukin-4 receptor subunit α. Antibody pharmacological agent targeting this protein.

duvelisib — phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Interaction

Drug-target interaction between duvelisib and phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta. Synthetic organic pharmacological agent targeting this protein.

duvelisib — phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Interaction

Drug-target interaction between duvelisib and phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma. Synthetic organic pharmacological agent targeting this protein.

dydrogesterone — Progesterone receptor Interaction

Drug-target interaction between dydrogesterone and Progesterone receptor. Synthetic organic pharmacological agent targeting this protein.

ebronucimab — proprotein convertase subtilisin/kexin type 9 Interaction

Drug-target interaction between ebronucimab and proprotein convertase subtilisin/kexin type 9. Antibody pharmacological agent targeting this protein.

edoxaban — coagulation factor X Interaction

Drug-target interaction between edoxaban and coagulation factor X. Synthetic organic pharmacological agent targeting this protein.

efalizumab — integrin, alpha L subunit (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) Interaction

Drug-target interaction between efalizumab and integrin, alpha L subunit (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide). Antibody pharmacological agent targeting t

efgartigimod alfa — Fc fragment of IgG receptor and transporter Interaction

Drug-target interaction between efgartigimod alfa and Fc fragment of IgG receptor and transporter. Antibody pharmacological agent targeting this protein.

eflornithine — Ornithine decarboxylase Interaction

Drug-target interaction between eflornithine and Ornithine decarboxylase. Synthetic organic pharmacological agent targeting this protein.

elagolix — GnRH1 receptor Interaction

Drug-target interaction between elagolix and GnRH1 receptor. Synthetic organic pharmacological agent targeting this protein.

eletriptan — 5-HT1B receptor Interaction

Drug-target interaction between eletriptan and 5-HT1B receptor. Synthetic organic pharmacological agent targeting this protein.

eletriptan — 5-HT1D receptor Interaction

Drug-target interaction between eletriptan and 5-HT1D receptor. Synthetic organic pharmacological agent targeting this protein.