Drug Targets
Comprehensive drug target database including GPCRs, ion channels, nuclear receptors, kinases, and enzymes.
Browse the pages below for detailed information.
DNA polymerase gamma, catalytic subunit
DNA polymerase gamma, catalytic subunit — Enzyme drug target in the DNA polymerases family.
DNA polymerase theta
DNA polymerase theta — Enzyme drug target in the DNA polymerases family.
DNA topoisomerase I
DNA topoisomerase I — Enzyme drug target in the DNA topoisomerases family.
DNA topoisomerase II alpha
DNA topoisomerase II alpha — Enzyme drug target in the DNA topoisomerases family.
Dopamine beta-hydroxylase (dopamine beta-monooxygenase)
Dopamine beta-hydroxylase (dopamine beta-monooxygenase) — Enzyme drug target in the Catecholamine turnover family.
DOT1 like histone lysine methyltransferase
DOT1 like histone lysine methyltransferase — Enzyme drug target in the Histone methyltransferases (HMTs) family.
doublecortin like kinase 1
doublecortin like kinase 1 — Enzyme drug target in the DCAMKL family family.
doublecortin like kinase 2
doublecortin like kinase 2 — Enzyme drug target in the DCAMKL family family.
doublecortin like kinase 3
doublecortin like kinase 3 — Enzyme drug target in the DCAMKL family family.
DP1 receptor
DP1 receptor — GPCR drug target in the Prostanoid receptors family.
DP2 receptor
DP2 receptor — GPCR drug target in the Prostanoid receptors family.
DRA
DRA — Transporter drug target in the Chloride/bicarbonate exchangers family.
DTDST
DTDST — Transporter drug target in the Selective sulphate transporters family.
dual oxidase 1
dual oxidase 1 — Enzyme drug target in the NADPH oxidases family.
dual oxidase 2
dual oxidase 2 — Enzyme drug target in the NADPH oxidases family.
dual serine/threonine and tyrosine protein kinase
dual serine/threonine and tyrosine protein kinase — Enzyme drug target in the Other-unique family family.
dual specificity tyrosine phosphorylation regulated kinase 1A
dual specificity tyrosine phosphorylation regulated kinase 1A — Enzyme drug target in the Dyrk1 subfamily family.
dual specificity tyrosine phosphorylation regulated kinase 1B
dual specificity tyrosine phosphorylation regulated kinase 1B — Enzyme drug target in the Dyrk1 subfamily family.
dual specificity tyrosine phosphorylation regulated kinase 2
dual specificity tyrosine phosphorylation regulated kinase 2 — Enzyme drug target in the Dyrk2 subfamily family.
dual specificity tyrosine phosphorylation regulated kinase 3
dual specificity tyrosine phosphorylation regulated kinase 3 — Enzyme drug target in the Dyrk2 subfamily family.
dual specificity tyrosine phosphorylation regulated kinase 4
dual specificity tyrosine phosphorylation regulated kinase 4 — Enzyme drug target in the Dyrk1 subfamily family.
E-LOX
E-LOX — Enzyme drug target in the Lipoxygenases family.
Ecto-5'-Nucleotidase
Ecto-5'-Nucleotidase — Enzyme drug target in the Adenosine turnover family.
ectonucleoside triphosphate diphosphohydrolase 1
ectonucleoside triphosphate diphosphohydrolase 1 — Enzyme drug target in the Hydrolases & Lipases family.
ectonucleoside triphosphate diphosphohydrolase 2
ectonucleoside triphosphate diphosphohydrolase 2 — Enzyme drug target in the Hydrolases & Lipases family.
ectonucleotide pyrophosphatase/phosphodiesterase 1
ectonucleotide pyrophosphatase/phosphodiesterase 1 — Enzyme drug target in the Cyclic GMP-AMP turnover family.
egl-9 family hypoxia inducible factor 1
egl-9 family hypoxia inducible factor 1 — Enzyme drug target in the Prolyl hydroxylases family.
egl-9 family hypoxia inducible factor 2
egl-9 family hypoxia inducible factor 2 — Enzyme drug target in the Prolyl hydroxylases family.
egl-9 family hypoxia inducible factor 3
egl-9 family hypoxia inducible factor 3 — Enzyme drug target in the Prolyl hydroxylases family.
elastase, neutrophil expressed
elastase, neutrophil expressed — Enzyme drug target in the S1: Chymotrypsin family.
Electrogenic sodium bicarbonate cotransporter 1
Electrogenic sodium bicarbonate cotransporter 1 — Transporter drug target in the Sodium-dependent HCO3- transporters family.
Electrogenic sodium bicarbonate cotransporter 4
Electrogenic sodium bicarbonate cotransporter 4 — Transporter drug target in the Sodium-dependent HCO3- transporters family.
Electroneutral sodium bicarbonate cotransporter 1
Electroneutral sodium bicarbonate cotransporter 1 — Transporter drug target in the Sodium-dependent HCO3- transporters family.
Electroneutral sodium bicarbonate cotransporter 2
Electroneutral sodium bicarbonate cotransporter 2 — Transporter drug target in the Sodium-dependent HCO3- transporters family.
elongator acetyltransferase complex subunit 3
elongator acetyltransferase complex subunit 3 — Enzyme drug target in the Histone acetyltransferases (HATs) family.
embryonic ectoderm development
embryonic ectoderm development — Enzyme drug target in the Neutral sphingomyelinase coupling factors family.
Endoplasmic reticulum aminopeptidase 1
Endoplasmic reticulum aminopeptidase 1 — Enzyme drug target in the M1: Aminopeptidase N family.
Endoplasmic reticulum aminopeptidase 2
Endoplasmic reticulum aminopeptidase 2 — Enzyme drug target in the M1: Aminopeptidase N family.
endoplasmic reticulum to nucleus signaling 1
endoplasmic reticulum to nucleus signaling 1 — Enzyme drug target in the IRE family family.
endoplasmic reticulum to nucleus signaling 2
endoplasmic reticulum to nucleus signaling 2 — Enzyme drug target in the IRE family family.
Endothelial NOS
Endothelial NOS — Enzyme drug target in the Nitric oxide synthases family.
Endothelin-converting enzyme 1
Endothelin-converting enzyme 1 — Enzyme drug target in the M13: Neprilysin family.
Endothelin-converting enzyme 2
Endothelin-converting enzyme 2 — Enzyme drug target in the M13: Neprilysin family.
enhancer of zeste 1 polycomb repressive complex 2 subunit
enhancer of zeste 1 polycomb repressive complex 2 subunit — Enzyme drug target in the Histone methyltransferases (HMTs) family.
enhancer of zeste 2 polycomb repressive complex 2 subunit
enhancer of zeste 2 polycomb repressive complex 2 subunit — Enzyme drug target in the Histone methyltransferases (HMTs) family.
EP1 receptor
EP1 receptor — GPCR drug target in the Prostanoid receptors family.
EP2 receptor
EP2 receptor — GPCR drug target in the Prostanoid receptors family.
EP3 receptor
EP3 receptor — GPCR drug target in the Prostanoid receptors family.
EP4 receptor
EP4 receptor — GPCR drug target in the Prostanoid receptors family.
epoxide hydrolase 2
epoxide hydrolase 2 — Enzyme drug target in the Hydrolases & Lipases family.
Equilibrative nucleoside transporter 1
Equilibrative nucleoside transporter 1 — Transporter drug target in the SLC29 family family.
Equilibrative nucleoside transporter 2
Equilibrative nucleoside transporter 2 — Transporter drug target in the SLC29 family family.
Equilibrative nucleoside transporter 3
Equilibrative nucleoside transporter 3 — Transporter drug target in the SLC29 family family.
Erythrocyte urea transporter
Erythrocyte urea transporter — Transporter drug target in the SLC14 family of facilitative urea transporters family.
Estrogen receptor-α
Estrogen receptor-α — Nuclear Receptor drug target in the 3A. Estrogen receptors family.
Estrogen receptor-β
Estrogen receptor-β — Nuclear Receptor drug target in the 3A. Estrogen receptors family.
Estrogen-related receptor-α
Estrogen-related receptor-α — Nuclear Receptor drug target in the 3B. Estrogen-related receptors family.
Estrogen-related receptor-β
Estrogen-related receptor-β — Nuclear Receptor drug target in the 3B. Estrogen-related receptors family.
Estrogen-related receptor-γ
Estrogen-related receptor-γ — Nuclear Receptor drug target in the 3B. Estrogen-related receptors family.
ETA receptor
ETA receptor — GPCR drug target in the Endothelin receptors family.