Pharmaceutical Chemistry

Drug Targets

Comprehensive drug target database including GPCRs, ion channels, nuclear receptors, kinases, and enzymes.

Browse the pages below for detailed information.

interleukin 1 receptor associated kinase 3

interleukin 1 receptor associated kinase 3 — Enzyme drug target in the Interleukin-1 receptor-associated kinase (IRAK) family family.

interleukin 1 receptor associated kinase 4

interleukin 1 receptor associated kinase 4 — Enzyme drug target in the Interleukin-1 receptor-associated kinase (IRAK) family family.

iodothyronine deiodinase 1

iodothyronine deiodinase 1 — Enzyme drug target in the Thyroid hormone turnover family.

iodothyronine deiodinase 2

iodothyronine deiodinase 2 — Enzyme drug target in the Thyroid hormone turnover family.

iodothyronine deiodinase 3

iodothyronine deiodinase 3 — Enzyme drug target in the Thyroid hormone turnover family.

iodotyrosine deiodinase

iodotyrosine deiodinase — Enzyme drug target in the Thyroid hormone turnover family.

IP receptor

IP receptor — GPCR drug target in the Prostanoid receptors family.

IP3 kinase A

IP3 kinase A — Enzyme drug target in the Inositol 1,4,5-trisphosphate 3-kinases family.

IP3 kinase B

IP3 kinase B — Enzyme drug target in the Inositol 1,4,5-trisphosphate 3-kinases family.

IP3 kinase C

IP3 kinase C — Enzyme drug target in the Inositol 1,4,5-trisphosphate 3-kinases family.

iPLA2-G6

iPLA2-G6 — Enzyme drug target in the Phospholipase A2 family.

isocitrate dehydrogenase (NADP(+)) 1

isocitrate dehydrogenase (NADP(+)) 1 — Enzyme drug target in the Isocitrate dehydrogenases family.

isocitrate dehydrogenase (NADP(+)) 2

isocitrate dehydrogenase (NADP(+)) 2 — Enzyme drug target in the Isocitrate dehydrogenases family.

isopentenyl-diphosphate Δ-isomerase 1

isopentenyl-diphosphate Δ-isomerase 1 — Enzyme drug target in the Lanosterol biosynthesis pathway family.

isopentenyl-diphosphate Δ-isomerase 2

isopentenyl-diphosphate Δ-isomerase 2 — Enzyme drug target in the Lanosterol biosynthesis pathway family.

Janus kinase 1

Janus kinase 1 — Enzyme drug target in the Janus kinase (JakA) family family.

Janus kinase 2

Janus kinase 2 — Enzyme drug target in the Janus kinase (JakA) family family.

Janus kinase 3

Janus kinase 3 — Enzyme drug target in the Janus kinase (JakA) family family.

jumonji domain containing 1C

jumonji domain containing 1C — Enzyme drug target in the Histone acetyltransferases (HATs) family.

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

jumonji domain containing 6, arginine demethylase and lysine hydroxylase — Enzyme drug target in the Histone demethylases family.

K-Cl cotransporter 1

K-Cl cotransporter 1 — Transporter drug target in the SLC12 family of cation-coupled chloride transporters family.

K-Cl cotransporter 2

K-Cl cotransporter 2 — Transporter drug target in the SLC12 family of cation-coupled chloride transporters family.

K-Cl cotransporter 3

K-Cl cotransporter 3 — Transporter drug target in the SLC12 family of cation-coupled chloride transporters family.

K-Cl cotransporter 4

K-Cl cotransporter 4 — Transporter drug target in the SLC12 family of cation-coupled chloride transporters family.

kalirin RhoGEF kinase

kalirin RhoGEF kinase — Enzyme drug target in the Trio family family.

kallikrein 1

kallikrein 1 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein B1

kallikrein B1 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein related peptidase 14

kallikrein related peptidase 14 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein related peptidase 2

kallikrein related peptidase 2 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein related peptidase 3

kallikrein related peptidase 3 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein related peptidase 4

kallikrein related peptidase 4 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein related peptidase 5

kallikrein related peptidase 5 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein related peptidase 6

kallikrein related peptidase 6 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein related peptidase 7

kallikrein related peptidase 7 — Enzyme drug target in the S1: Chymotrypsin family.

kallikrein related peptidase 8

kallikrein related peptidase 8 — Enzyme drug target in the S1: Chymotrypsin family.

katanin catalytic subunit A1

katanin catalytic subunit A1 — Enzyme drug target in the AAA ATPases family.

KBAT

KBAT — Transporter drug target in the Other SLC26 anion exchangers family.

kelch domain containing 2

kelch domain containing 2 — Enzyme drug target in the E3 ubiquitin ligase components family.

kelch like family member 12

kelch like family member 12 — Enzyme drug target in the E3 ubiquitin ligase components family.

ketohexokinase

ketohexokinase — Enzyme drug target in the Sugar kinases family.

Kidney urea transporter

Kidney urea transporter — Transporter drug target in the SLC14 family of facilitative urea transporters family.

Kidney-specific Na-K-Cl symporter

Kidney-specific Na-K-Cl symporter — Transporter drug target in the SLC12 family of cation-coupled chloride transporters family.

kinase suppressor of ras 1

kinase suppressor of ras 1 — Enzyme drug target in the RAF family family.

kinase suppressor of ras 2

kinase suppressor of ras 2 — Enzyme drug target in the RAF family family.

kisspeptin receptor

kisspeptin receptor — GPCR drug target in the Kisspeptin receptor family.

klotho

klotho — Enzyme drug target in the Glycosidases family.

KRAS

KRAS — Enzyme drug target in the RAS subfamily family.

kynurenine 3-monooxygenase

kynurenine 3-monooxygenase — Enzyme drug target in the Kynurenine 3-monooxygenase family.

L-Arginine decarboxylase

L-Arginine decarboxylase — Enzyme drug target in the Decarboxylases family.

L-Aromatic amino-acid decarboxylase

L-Aromatic amino-acid decarboxylase — Enzyme drug target in the Decarboxylases family.

L-Cysteine:2-oxoglutarate aminotransferase

L-Cysteine:2-oxoglutarate aminotransferase — Enzyme drug target in the Hydrogen sulphide synthesis family.

L-PGDS

L-PGDS — Enzyme drug target in the Prostaglandin synthases family.

L-Phenylalanine hydroxylase

L-Phenylalanine hydroxylase — Enzyme drug target in the Catecholamine turnover family.

L-Tryptophan hydroxylase 1

L-Tryptophan hydroxylase 1 — Enzyme drug target in the Amino acid hydroxylases family.

L-Tryptophan hydroxylase 2

L-Tryptophan hydroxylase 2 — Enzyme drug target in the Amino acid hydroxylases family.

L-type amino acid transporter 1

L-type amino acid transporter 1 — Transporter drug target in the SLC7 family family.

L-type amino acid transporter 2

L-type amino acid transporter 2 — Transporter drug target in the SLC7 family family.

L-type amino acid transporter 3

L-type amino acid transporter 3 — Transporter drug target in the SLC43 family of large neutral amino acid transporters family.

L-type amino acid transporter 4

L-type amino acid transporter 4 — Transporter drug target in the SLC43 family of large neutral amino acid transporters family.

L-Tyrosine hydroxylase

L-Tyrosine hydroxylase — Enzyme drug target in the Catecholamine turnover family.